| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | The Girl On the Train (2016) | £3,412,472 | £6,696,699 | £13,654,644 | -51% | 2 |
| 2 (new) |  | Inferno (2016) | £2,970,026 | £2,970,026 | £2,970,026 | new | 1 |
| 3 (new) |  | Storks (2016) | £2,247,038 | £2,247,038 | £2,247,038 | new | 1 |
| 4 (new) |  | Miss Saigon 25th Anniversary Performance (2016) | £2,033,031 | £2,033,031 | £2,033,031 | new | 1 |
| 5 (2) |  | Bridget Jones's Baby (2016) | £1,888,985 | £4,125,400 | £41,991,552 | -37% | 5 |
| 6 (3) |  | Miss Peregrines Home For Peculiar Children (2016) | £1,313,861 | £2,046,390 | £8,763,435 | -41% | 3 |
| 7 (4) |  | Deepwater Horizon (2016) | £456,456 | £1,028,762 | £4,852,229 | -54% | 3 |
| 8 (5) |  | The Magnificent Seven (2016) | £212,000 | £523,913 | £5,895,017 | -59% | 4 |
| 9 (6) |  | Finding Dory (2016) | £187,951 | £221,066 | £42,251,360 | -33% | 12 |
| 10 (new) |  | American Honey (2016) | £175,383 | £175,383 | £175,383 | new | 1 |
| 11 (11) | | My Scientology Movie (2016) | £121,882 | £663,521 | £770,241 | 12% | 2 |
| 12 (15) |  | The Secret Life of Pets (2016) | £97,517 | £103,786 | £35,316,094 | 28% | 12 |
| 13 (new) | | Golden Age: Bolshoi 2016 (2016) | £86,853 | £86,853 | £86,853 | new | 1 |
| 14 (10) |  | Don't Breathe (2016) | £76,234 | £144,281 | £3,719,220 | -40% | 6 |
| 15 (16) |  | The BFG (2016) | £69,247 | £78,091 | £30,132,869 | 1% | 13 |
| 16 (re) |  | Supersonic (2016) | £39,718 | £39,718 | £667,591 | re | 2 |
| 17 (7) | | War On Everyone (2016) | £34,811 | £141,560 | £329,124 | -81% | 2 |
| 18 (new) |  | Kochaj (2016) | £29,037 | £29,037 | £29,037 | new | 1 |
| 19 (new) | | Gautas Iskvietimas 3 (2016) | £22,999 | £22,999 | £22,999 | new | 1 |
| 20 (20) |  | The Beatles: Eight Days a Week - The Touring Years (2016) | £11,374 | £38,233 | £1,021,373 | -56% | 5 |
| 21 (21) |  | Brotherhood (2016) | £11,125 | £21,441 | £3,680,473 | -47% | 7 |
| 22 (18) |  | The Girl With All the Gifts (2016) | £11,081 | £40,455 | £1,051,758 | -70% | 4 |
| 23 (new) | | Lock (2016) | £9,522 | £9,522 | £9,522 | new | 1 |
| 24 (new) | | The Flag (2016) | £9,222 | £9,222 | £9,222 | new | 1 |
| 25 (new) | | Tutak Tutak Tutiya (2016) | £6,972 | £6,972 | £6,972 | new | 1 |
| 26 (22) |  | The Infiltrator (2016) | £6,145 | £17,341 | £1,056,807 | -69% | 5 |
| 27 (24) |  | Anthropoid (2016) | £5,897 | £21,519 | £772,105 | -59% | 6 |
| 28 (25) |  | Swallows and Amazons (2016) | £4,626 | £7,332 | £3,021,437 | -61% | 9 |
| 29 (27) | | Under the Shadow (2016) | £4,180 | £8,207 | £59,638 | -26% | 3 |
| 30 (29) |  | Jason Bourne (2016) | £2,447 | £6,743 | £23,112,337 | -36% | 12 |
| 31 (26) | | The Greasy Strangler (2016) | £2,397 | £3,589 | £12,652 | -74% | 2 |
| 32 (32) | | The Deep Blue Sea: NT Live 2016 (2016) | £2,233 | £4,026 | £717,526 | 13% | 6 |
| 33 (new) | | Oru Muthassi Gadha (2016) | £2,100 | £2,100 | £2,100 | new | 1 |
| 34 (new) |  | Kate Plays Christine (2016) | £1,477 | £1,477 | £1,477 | new | 1 |
| 35 (new) |  | MSG the Warrior: Lion Heart (2016) | £1,475 | £1,475 | £1,475 | new | 1 |
| 36 (re) | | King Lear: RSC Live 2016 (2016) | £1,386 | £1,386 | £405,467 | re | 1 |
| 37 (re) |  | Absolutely Fabulous: The Movie (2016) | £1,209 | £1,209 | £16,042,647 | re | 13 |
| 38 (41) |  | Bobby Sands 66 Days (2016) | £716 | £2,377 | £238,358 | 77% | 11 |
| 39 (new) | | Aatishbaazi Ishq (2016) | £579 | £579 | £579 | new | 1 |
| 40 (new) | | Kavi Udheshichathu (2016) | £530 | £530 | £530 | new | 1 |
| 41 (re) | | Still Loved (2016) | £252 | £252 | £3,748 | re | 1 |
| 42 (33) | | The Threepenny Opera: NT Live 2016 (2016) | £245 | £5,652 | £334,987 | -81% | 4 |
| 43 (new) |  | Rekka (2016) | £232 | £232 | £232 | new | 1 |
| 44 (new) | | Sky Ladder (2016) | £180 | £180 | £180 | new | 1 |