| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (2) |  | Finding Dory () | £2,868,459 | £5,045,472 | £32,358,650 | 11% | 4 |
| 2 (1) |  | Suicide Squad (2016) | £2,549,043 | £5,454,505 | £27,668,748 | -40% | 3 |
| 3 (new) |  | David Brent: Life On the Road (2016) | £1,460,290 | £1,460,290 | £1,460,290 | new | 1 |
| 4 (3) |  | Jason Bourne (2016) | £1,263,975 | £2,256,666 | £19,718,874 | -14% | 4 |
| 5 (4) |  | The BFG () | £1,236,002 | £2,257,687 | £25,767,760 | 10% | 5 |
| 6 (new) | | Lights Out () | £1,126,543 | £1,126,543 | £1,126,543 | new | 1 |
| 7 (6) |  | Pete's Dragon () | £794,362 | £1,545,248 | £2,389,338 | -6% | 2 |
| 8 (new) |  | Swallows and Amazons () | £676,175 | £676,175 | £676,175 | new | 1 |
| 9 (new) |  | Nine Lives () | £636,804 | £636,804 | £636,804 | new | 1 |
| 10 (9) |  | Star Trek: Beyond (2016) | £400,350 | £776,708 | £14,988,337 | -16% | 5 |
| 11 (5) |  | Mike and Dave Need Wedding Dates () | £397,478 | £959,803 | £2,028,325 | -63% | 2 |
| 12 (7) |  | Nerve () | £392,244 | £942,309 | £1,745,766 | -51% | 2 |
| 13 (8) |  | The Shallows (2016) | £381,697 | £922,423 | £1,723,386 | -52% | 2 |
| 14 (10) |  | The Secret Life of Pets (2016) | £352,252 | £654,446 | £33,712,464 | 19% | 9 |
| 15 (13) |  | Ghostbusters (2016) | £76,718 | £168,514 | £10,554,557 | -32% | 6 |
| 16 (new) |  | Asterix: The Mansions of the Gods (2015) | £55,818 | £55,818 | £55,818 | new | 1 |
| 17 (36) |  | Alice Through the Looking Glass (2016) | £55,005 | £56,582 | £9,726,262 | 99% | 12 |
| 18 (new) |  | The Childhood of a Leader (2016) | £52,613 | £52,613 | £52,613 | new | 1 |
| 19 (new) |  | Happy Bhag Jayegi (2016) | £48,507 | £48,507 | £48,507 | new | 1 |
| 20 (16) |  | Absolutely Fabulous: The Movie () | £30,946 | £111,016 | £15,879,609 | -36% | 8 |
| 21 (19) |  | Bobby Sands 66 Days () | £26,464 | £49,375 | £168,010 | -2% | 3 |
| 22 (new) | | Tickled () | £25,602 | £25,602 | £25,602 | new | 1 |
| 23 (new) | | Blinky Bill: The Movie () | £21,304 | £21,304 | £21,304 | new | 1 |
| 24 (21) |  | The Legend of Tarzan () | £17,002 | £35,277 | £9,172,210 | -6% | 7 |
| 25 (new) | | Viva () | £15,234 | £15,234 | £15,234 | new | 1 |
| 26 (new) | | Get Squirrely () | £13,832 | £13,832 | £13,832 | new | 1 |
| 27 (new) |  | Main Teri Tu Mera () | £9,140 | £9,140 | £9,140 | new | 1 |
| 28 (22) |  | Now You See Me 2 (2016) | £9,043 | £24,279 | £6,282,532 | -41% | 7 |
| 29 (re) |  | Spectre () | £8,686 | £8,686 | £95,200,787 | re | 20 |
| 30 (re) |  | Love and Friendship () | £3,968 | £3,968 | £1,760,136 | re | 12 |
| 31 (35) |  | The Jungle Book () | £3,337 | £6,476 | £46,120,397 | 76% | 19 |
| 32 (28) | | Almeida Live: Richard III 2016 (2016) | £2,525 | £9,756 | £413,989 | -8% | 4 |
| 33 (26) | | Born to Be Blue () | £1,791 | £5,286 | £35,952 | -58% | 4 |
| 34 (new) | | Black (2016) | £1,760 | £1,760 | £1,760 | new | 1 |
| 35 (new) | | Cosmos () | £1,573 | £1,573 | £1,573 | new | 1 |
| 36 (new) | | Gajalu () | £1,289 | £1,289 | £1,289 | new | 1 |
| 37 (33) | | The Carer () | £1,185 | £4,282 | £11,708 | 6% | 3 |
| 38 (17) |  | Branagh Theatre Live: Romeo and Juliet 2016 () | £1,019 | £3,366 | £814,629 | -97% | 7 |
| 39 (new) | | Almost Holy () | £978 | £978 | £978 | new | 1 |
| 40 (new) | | Half Ticket (2016) | £868 | £868 | £868 | new | 1 |
| 41 (24) | | The Confession () | £758 | £5,436 | £14,993 | -92% | 2 |
| 42 (25) | | My Best Friends Wedding (2016) | £495 | £3,395 | £9,428 | -92% | 2 |
| 43 (20) | | The Idol () | £363 | £5,013 | £24,870 | -98% | 2 |
| 44 (39) |  | Tale of Tales (2015) | £304 | £869 | £394,300 | 47% | 10 |
| 45 (new) |  | Clean Hands () | £269 | £269 | £269 | new | 1 |
| 46 (31) |  | Me Before You () | £175 | £7,388 | £9,600,948 | -90% | 12 |
| 47 (30) |  | ID2: Shadwell Army () | £68 | £1,380 | £3,642 | -97% | 2 |
| 48 (new) |  | 400 Days (2016) | £44 | £44 | £44 | new | 1 |