| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | The Secret Life of Pets (2016) | £3,624,751 | £5,645,713 | £22,261,438 | -24% | 3 |
| 2 (new) |  | The Legend of Tarzan (2016) | £3,570,350 | £3,570,350 | £3,570,350 | new | 1 |
| 3 (new) |  | Now You See Me 2 (2016) | £2,964,641 | £2,964,641 | £2,964,641 | new | 1 |
| 4 (2) |  | Absolutely Fabulous: The Movie (2016) | £2,316,349 | £5,736,245 | £9,779,204 | -43% | 2 |
| 5 (3) |  | Central Intelligence (2016) | £1,342,004 | £2,630,482 | £5,680,743 | -56% | 2 |
| 6 (new) |  | Sultan (2016) | £1,048,417 | £1,048,417 | £1,048,417 | new | 1 |
| 7 (4) |  | Independence Day: Resurgence (2016) | £782,975 | £1,754,950 | £10,910,774 | -61% | 3 |
| 8 (5) |  | The Conjuring 2: The Enfield Case (2016) | £401,155 | £854,750 | £10,312,076 | -51% | 4 |
| 9 (new) |  | The Neon Demon (2016) | £126,996 | £126,996 | £126,996 | new | 1 |
| 10 (6) |  | Me Before You (2016) | £126,907 | £353,153 | £9,285,210 | -64% | 6 |
| 11 (new) |  | Maggies Plan (2016) | £102,534 | £102,534 | £102,534 | new | 1 |
| 12 (8) |  | The Jungle Book (2016) | £70,891 | £97,614 | £45,836,354 | -11% | 13 |
| 13 (11) |  | Zootopia (2016) | £65,064 | £76,289 | £23,786,172 | 7% | 13 |
| 14 (7) |  | The Nice Guys (2016) | £49,553 | £97,307 | £3,792,002 | -50% | 6 |
| 15 (9) |  | Alice Through the Looking Glass (2016) | £37,526 | £68,821 | £9,613,602 | -53% | 7 |
| 16 (new) | | Weiner (2016) | £16,577 | £16,577 | £16,577 | new | 1 |
| 17 (14) |  | Tale of Tales (2015) | £14,458 | £35,529 | £340,224 | -49% | 4 |
| 18 (new) |  | Cold War 2 (2016) | £10,966 | £10,966 | £10,966 | new | 1 |
| 19 (16) |  | Love and Friendship (2016) | £10,433 | £47,877 | £1,695,096 | -57% | 7 |
| 20 (25) |  | Our Kind of Traitor (2016) | £6,844 | £10,617 | £1,208,947 | 57% | 9 |
| 21 (17) | | Notes On Blindness (2016) | £6,224 | £26,126 | £46,175 | -69% | 2 |
| 22 (re) |  | Branagh Theatre Live: Romeo and Juliet 2016 (2016) | £5,095 | £5,095 | £720,891 | re | 1 |
| 23 (19) |  | Adult Life Skills (2016) | £2,182 | £7,063 | £44,989 | -72% | 3 |
| 24 (new) | | Hide and Seek (2016) | £1,989 | £1,989 | £1,989 | new | 1 |
| 25 (new) | | The Wait (2016) | £1,553 | £1,553 | £1,553 | new | 1 |
| 26 (20) |  | Florence Foster Jenkins (2016) | £1,172 | £8,237 | £3,158,125 | -73% | 10 |
| 27 (29) |  | A Hologram For the King (2016) | £1,022 | £1,840 | £794,057 | -10% | 8 |
| 28 (27) |  | Remainder (2016) | £325 | £1,809 | £29,465 | -85% | 3 |
| 29 (23) |  | Eye In the Sky (2016) | £268 | £4,257 | £5,043,517 | -92% | 13 |
| 30 (34) |  | Thomas & Friends: The Great Race (2016) | £153 | £153 | £298,175 | -55% | 8 |
| 31 (32) |  | Versus: The Life and Films of Ken Loach (2016) | £118 | £1,602 | £37,214 | -80% | 6 |