| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (3) |  | Me Before You () | £1,453,859 | £2,687,343 | £4,478,000 | -19% | 2 |
| 2 (2) |  | Teenage Mutant Ninja Turtles: Out of the Shadows () | £840,868 | £1,306,322 | £4,801,767 | -76% | 2 |
| 3 (4) |  | Alice Through the Looking Glass (2016) | £832,914 | £1,303,636 | £8,306,639 | -38% | 3 |
| 4 (1) |  | Warcraft () | £728,168 | £1,398,586 | £5,022,284 | -80% | 2 |
| 5 (5) |  | X-Men: Apocalypse (2016) | £703,505 | £1,212,595 | £17,067,686 | -44% | 4 |
| 6 (6) |  | The Nice Guys () | £641,684 | £1,228,012 | £2,232,634 | -36% | 2 |
| 7 (new) |  | The Boss (2016) | £594,672 | £594,672 | £594,672 | new | 1 |
| 8 (7) |  | The Angry Birds Movie () | £579,144 | £730,832 | £9,430,115 | -32% | 5 |
| 9 (new) |  | Mother's Day () | £419,532 | £419,532 | £419,532 | new | 1 |
| 10 (8) |  | The Jungle Book () | £412,358 | £530,329 | £45,111,681 | -28% | 9 |
| 11 (9) |  | Money Monster () | £179,332 | £391,706 | £2,387,743 | -51% | 3 |
| 12 (12) |  | Love and Friendship () | £170,296 | £328,821 | £1,172,393 | -29% | 3 |
| 13 (11) |  | Captain America: Civil War () | £147,485 | £237,351 | £36,771,782 | -43% | 7 |
| 14 (new) | | When Marnie Was There (2014) | £99,352 | £99,352 | £99,352 | new | 1 |
| 15 (13) |  | Zootopia () | £87,842 | £99,009 | £23,560,056 | -54% | 11 |
| 16 (new) | | Where to Invade Next () | £85,505 | £85,505 | £85,505 | new | 1 |
| 17 (new) | | Embrace of the Serpent (2016) | £41,387 | £41,387 | £41,387 | new | 1 |
| 18 (new) | | Te3n (2016) | £35,905 | £35,905 | £35,905 | new | 1 |
| 19 (new) | | Learning to Drive () | £31,970 | £31,970 | £31,970 | new | 1 |
| 20 (new) |  | Miracles From Heaven () | £20,420 | £20,420 | £20,420 | new | 1 |
| 21 (17) |  | Florence Foster Jenkins () | £18,172 | £56,036 | £3,047,605 | -35% | 6 |
| 22 (re) |  | The Audience: NT Live 2013 () | £16,139 | £16,139 | £2,199,023 | re | 1 |
| 23 (19) |  | Our Kind of Traitor (2016) | £15,269 | £28,751 | £1,132,748 | -32% | 5 |
| 24 (new) |  | Fire At Sea (2016) | £13,115 | £13,115 | £13,115 | new | 1 |
| 25 (20) |  | Eye In the Sky () | £9,579 | £25,532 | £4,994,921 | -38% | 9 |
| 26 (new) | | Dhulla Bhatti () | £5,522 | £5,522 | £5,522 | new | 1 |
| 27 (18) |  | Thomas & Friends: The Great Race (2016) | £4,568 | £5,498 | £283,557 | -82% | 4 |
| 28 (36) |  | The Man Who Knew Infinity (2016) | £4,153 | £9,449 | £530,413 | 95% | 10 |
| 29 (23) |  | A Hologram For the King (2016) | £4,037 | £13,789 | £762,322 | -66% | 4 |
| 30 (32) | | Bobby () | £3,241 | £4,331 | £9,067 | 69% | 3 |
| 31 (new) | | Globe On Screen: The Merchant of Venice Shakespeares Globe 2015 () | £2,964 | £2,964 | £2,964 | new | 1 |
| 32 (new) |  | Once Upon a Time In Amritsar (2016) | £2,595 | £2,595 | £2,595 | new | 1 |
| 33 (new) | | The Stanford Prison Experiment (2015) | £1,790 | £1,790 | £1,790 | new | 1 |
| 34 (22) |  | Versus: The Life and Films of Ken Loach (2016) | £1,542 | £13,506 | £25,960 | -88% | 2 |
| 35 (31) |  | Golden Years () | £1,370 | £3,597 | £62,515 | 14% | 6 |
| 36 (27) |  | Eddie the Eagle () | £1,131 | £4,192 | £8,626,520 | -76% | 11 |
| 37 (re) | | Matthew Bourne's the Car Man 2015 (2016) | £762 | £762 | £83,587 | re | 7 |
| 38 (29) |  | Departure (2016) | £689 | £2,206 | £17,160 | -71% | 4 |
| 39 (re) | | Hamlet: RSC Live 2016 () | £632 | £632 | £254,056 | re | 1 |
| 40 (re) | | A View From the Bridge: NT Live 2015 () | £496 | £496 | £1,341,383 | re | 11 |
| 41 (re) | | Exhibition On Screen: Painting the Modern Garden - Monet to Matisse () | £340 | £340 | £201,520 | re | 1 |
| 42 (33) |  | Bastille Day () | £173 | £412 | £1,990,430 | -59% | 8 |
| 43 (34) |  | High Rise (2016) | £78 | £606 | £1,965,980 | -81% | 13 |