| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Gullivers Travels () | £7,028,747 | £7,028,747 | £7,028,747 | new | 1 |
| 2 (1) |  | Little Fockers (2010) | £2,614,802 | £8,123,918 | £11,159,635 | -14% | 2 |
| 3 (new) |  | Love and Other Drugs () | £1,606,253 | £1,606,253 | £1,606,253 | new | 1 |
| 4 (new) |  | The Way Back () | £1,327,650 | £1,327,650 | £1,327,650 | new | 1 |
| 5 (3) |  | TRON Legacy (2010) | £1,259,569 | £3,584,617 | £8,371,361 | 56% | 3 |
| 6 (2) |  | The Chronicles of Narnia: The Voyage of the Dawn Treader (2010) | £1,207,264 | £3,785,959 | £11,263,418 | 23% | 4 |
| 7 (4) |  | Harry Potter and the Deathly Hallows Part 1 () | £1,040,826 | £2,119,836 | £48,914,777 | 60% | 7 |
| 8 (6) |  | Megamind () | £612,327 | £1,695,090 | £8,378,843 | 50% | 5 |
| 9 (7) |  | The Tourist () | £396,758 | £1,083,209 | £4,702,790 | 58% | 4 |
| 10 (8) |  | Animals United (2010) | £243,442 | £751,387 | £1,736,166 | 35% | 3 |
| 11 (10) |  | Burlesque (2010) | £183,023 | £673,641 | £1,610,646 | 55% | 3 |
| 12 (9) |  | Arthur and the Great Adventure () | £130,582 | £379,522 | £463,397 | 36% | 2 |
| 13 (5) |  | Tees Maar Khan () | £98,033 | £304,599 | £624,469 | -69% | 2 |
| 14 (12) |  | Fred: The Movie () | £85,877 | £294,930 | £838,616 | 48% | 3 |
| 15 (15) |  | Unstoppable (2010) | £31,407 | £89,019 | £4,614,199 | 41% | 6 |
| 16 (18) |  | Chatroom () | £15,629 | £47,891 | £52,816 | 68% | 2 |
| 17 (17) |  | Monsters () | £12,415 | £33,899 | £923,838 | 58% | 5 |
| 18 (19) |  | Another Year (2010) | £11,587 | £26,003 | £1,631,548 | 84% | 9 |
| 19 (20) |  | London Boulevard () | £4,359 | £10,460 | £1,343,913 | 64% | 6 |
| 20 (21) |  | Made In Dagenham (2010) | £1,537 | £5,050 | £3,670,508 | 61% | 14 |
| 21 (22) |  | Burke and Hare (2010) | £708 | £2,425 | £2,352,902 | 76% | 9 |
| 22 (28) |  | All Good Children () | £371 | £846 | £866 | 95% | 2 |
| 23 (23) |  | Cuckoo () | £133 | £585 | £2,297 | 20% | 3 |