| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Harry Potter and the Deathly Hallows Part 1 () | £8,344,776 | £14,938,159 | £33,257,880 | -54% | 2 |
| 2 (new) |  | Unstoppable (2010) | £1,714,871 | £1,714,871 | £1,714,871 | new | 1 |
| 3 (new) |  | London Boulevard () | £577,224 | £577,224 | £577,224 | new | 1 |
| 4 (2) |  | Due Date (2010) | £560,179 | £1,184,796 | £9,208,287 | -54% | 4 |
| 5 (new) |  | The American () | £411,707 | £411,707 | £411,707 | new | 1 |
| 6 (3) |  | Despicable Me (2010) | £241,944 | £327,803 | £19,394,633 | -63% | 7 |
| 7 (new) |  | The Girl Who Kicked the Hornets Nest () | £219,259 | £219,259 | £219,259 | new | 1 |
| 8 (5) |  | Jackass 3D () | £119,369 | £369,492 | £5,437,656 | -66% | 4 |
| 9 (4) |  | Skyline (2010) | £92,931 | £313,097 | £2,645,267 | -82% | 3 |
| 10 (new) |  | Machete () | £90,423 | £90,423 | £90,423 | new | 1 |
| 11 (new) | | Break Ke Baad (2010) | £85,708 | £85,708 | £85,708 | new | 1 |
| 12 (10) |  | Another Year (2010) | £59,505 | £168,760 | £1,443,577 | -63% | 4 |
| 13 (7) |  | Alpha and Omega (2010) | £58,293 | £66,580 | £2,939,702 | -70% | 6 |
| 14 (9) |  | The Social Network (2010) | £50,943 | £127,732 | £10,306,540 | -70% | 7 |
| 15 (8) |  | Guzaarish (2010) | £48,952 | £132,969 | £303,996 | -71% | 2 |