| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Due Date (2010) | £2,346,089 | £2,346,089 | £2,346,089 | new | 1 |
| 2 (new) |  | Jackass 3D (2010) | £1,696,909 | £1,696,909 | £1,696,909 | new | 1 |
| 3 (2) |  | Despicable Me (2010) | £1,177,507 | £1,794,041 | £16,863,318 | -54% | 4 |
| 4 (1) |  | Saw: The Final Chapter (2010) | £1,068,403 | £2,807,997 | £6,408,080 | -70% | 2 |
| 5 (3) |  | Paranormal Activity 2 (2010) | £687,747 | £1,577,652 | £9,876,254 | -63% | 3 |
| 6 (4) |  | Red (2010) | £595,362 | £1,212,919 | £5,553,877 | -50% | 3 |
| 7 (5) |  | The Social Network (2010) | £541,763 | £1,161,763 | £9,029,931 | -49% | 4 |
| 8 (new) |  | Let Me In (2010) | £488,172 | £488,172 | £488,172 | new | 1 |
| 9 (new) |  | Another Year (2010) | £355,626 | £355,626 | £355,626 | new | 1 |
| 10 (6) |  | Burke and Hare (2010) | £333,637 | £797,821 | £1,740,715 | -65% | 2 |
| 11 (new) | | Golmaal 3 (2010) | £259,611 | £259,611 | £259,611 | new | 1 |
| 12 (9) |  | The Kids Are All Right (2010) | £249,110 | £569,297 | £981,257 | -40% | 2 |
| 13 (8) |  | Alpha and Omega (2010) | £230,543 | £310,962 | £2,318,181 | -50% | 3 |
| 14 (7) |  | Legend of the Guardians: The Owls of Ga'hoole (2010) | £217,775 | £630,166 | £2,813,519 | -57% | 3 |
| 15 (new) |  | Action Replayy (2010) | £154,911 | £154,911 | £154,911 | new | 1 |