| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Killers () | £1,053,074 | £1,053,074 | £1,053,074 | new | 1 |
| 2 (1) |  | Sex and the City 2 () | £710,238 | £1,957,471 | £19,376,325 | -52% | 4 |
| 3 (3) |  | StreetDance 3D (2010) | £463,841 | £732,903 | £10,960,576 | -35% | 5 |
| 4 (4) |  | Prince of Persia: The Sands of Time (2010) | £389,715 | £662,339 | £8,035,706 | -23% | 5 |
| 5 (2) |  | Letters to Juliet (2010) | £304,319 | £669,686 | £1,463,111 | -62% | 2 |
| 6 (6) |  | Death At a Funeral () | £287,073 | £565,914 | £2,128,373 | -31% | 3 |
| 7 (new) |  | Wild Target (2010) | £282,498 | £282,498 | £282,498 | new | 1 |
| 8 (7) |  | Tooth Fairy (2010) | £249,578 | £322,369 | £3,375,473 | -32% | 4 |
| 9 (8) |  | Robin Hood () | £240,842 | £488,789 | £14,886,310 | -34% | 6 |
| 10 (5) |  | Brooklyn's Finest () | £203,204 | £467,589 | £935,868 | -57% | 2 |
| 11 (new) |  | Raavan (2010) | £125,130 | £125,130 | £125,130 | new | 1 |
| 12 (new) |  | Our Family Wedding () | £96,385 | £96,385 | £96,385 | new | 1 |
| 13 (12) |  | Greenberg (2010) | £77,979 | £165,002 | £283,806 | -34% | 2 |
| 14 (new) |  | Raavanan () | £72,599 | £72,599 | £72,599 | new | 1 |
| 15 (11) |  | Space Chimps 2: Zartog Strikes Back () | £71,355 | £86,047 | £1,565,128 | -42% | 4 |
| 16 (new) | | Please Give () | £49,940 | £49,940 | £49,940 | new | 1 |
| 17 (10) |  | 4.3.2.1 (2010) | £39,817 | £126,711 | £926,345 | -70% | 3 |
| 18 (16) |  | Four Lions () | £36,809 | £82,082 | £2,768,178 | -34% | 7 |
| 19 (new) |  | Macgruber (2010) | £34,367 | £34,367 | £34,367 | new | 1 |
| 20 (15) |  | The Killer Inside Me (2010) | £26,996 | £83,700 | £384,000 | -59% | 3 |
| 21 (new) | | Wild Grass (2010) | £16,184 | £16,184 | £16,184 | new | 1 |
| 22 (17) |  | Black Death () | £15,964 | £58,157 | £107,529 | -68% | 2 |
| 23 (new) | | His and Hers () | £12,343 | £12,343 | £12,343 | new | 1 |
| 24 (new) | | Ajami () | £8,468 | £8,468 | £8,468 | new | 1 |
| 25 (new) |  | Hierro () | £4,412 | £4,412 | £4,412 | new | 1 |
| 26 (new) | | Journey to Mecca (2010) | £3,141 | £3,141 | £3,141 | new | 1 |
| 27 (20) |  | Nanny Mcphee and the Big Bang (2010) | £3,139 | £3,496 | £16,379,041 | -41% | 13 |
| 28 (21) |  | The Ghost () | £2,358 | £11,321 | £4,047,319 | -54% | 10 |
| 29 (22) |  | American: The Bill Hicks Story () | £2,004 | £13,837 | £113,728 | -30% | 6 |
| 30 (23) |  | Kick-Ass () | £1,807 | £3,584 | £11,601,334 | 4% | 12 |
| 31 (26) | | Shed Your Tears and Walk Away () | £673 | £1,175 | £1,502 | 51% | 2 |
| 32 (new) | | Trash Humpers (2010) | £431 | £431 | £431 | new | 1 |
| 33 (24) | | The Infidel () | £45 | £2,186 | £589,698 | -96% | 11 |