| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Iron Man 2 () | £3,214,776 | £7,425,731 | £15,090,463 | -58% | 2 |
| 2 (new) |  | Furry Vengeance () | £1,778,050 | £1,778,050 | £1,778,050 | new | 1 |
| 3 (new) |  | A Nightmare On Elm Street () | £1,342,837 | £1,342,837 | £1,342,837 | new | 1 |
| 4 (new) |  | Hot Tub Time Machine (2010) | £904,959 | £904,959 | £904,959 | new | 1 |
| 5 (new) |  | The Back Up Plan (2010) | £710,201 | £710,201 | £710,201 | new | 1 |
| 6 (new) |  | Four Lions () | £608,608 | £608,608 | £608,608 | new | 1 |
| 7 (2) |  | How to Train Your Dragon (2010) | £516,120 | £1,132,769 | £16,405,622 | -39% | 6 |
| 8 (4) |  | The Last Song () | £336,815 | £872,580 | £1,552,278 | -50% | 2 |
| 9 (3) |  | Date Night () | £336,345 | £895,723 | £3,520,884 | -57% | 3 |
| 10 (5) |  | Clash of the Titans () | £291,352 | £736,938 | £19,938,794 | -56% | 6 |
| 11 (7) |  | The Ghost () | £277,171 | £628,592 | £3,590,029 | -49% | 4 |
| 12 (6) |  | Dear John (2010) | £231,793 | £663,339 | £5,290,957 | -62% | 4 |
| 13 (9) |  | Nanny Mcphee and the Big Bang (2010) | £171,063 | £465,493 | £16,097,021 | -56% | 7 |
| 14 (8) |  | Kick-Ass () | £137,416 | £430,316 | £11,421,640 | -66% | 6 |
| 15 (10) |  | House Full () | £96,898 | £283,611 | £546,363 | -63% | 2 |
| 16 (new) | | Badmaash Company () | £54,699 | £54,699 | £54,699 | new | 1 |
| 17 (12) |  | The Disappearance of Alice Creed () | £51,105 | £167,930 | £310,254 | -64% | 2 |
| 18 (11) |  | It's a Wonderful Afterlife (2010) | £37,347 | £155,633 | £969,515 | -79% | 3 |
| 19 (15) |  | Cemetery Junction (2010) | £21,515 | £72,469 | £1,401,471 | -72% | 3 |
| 20 (17) | | The Infidel () | £13,418 | £40,633 | £558,215 | -68% | 5 |
| 21 (new) |  | A Room and a Half () | £12,081 | £12,081 | £12,081 | new | 1 |
| 22 (new) |  | Virsa (2010) | £5,426 | £5,426 | £5,426 | new | 1 |
| 23 (16) |  | Centurion () | £5,212 | £46,057 | £287,002 | -88% | 3 |
| 24 (new) | | Sus (2010) | £1,826 | £1,826 | £1,826 | new | 1 |
| 25 (22) |  | No Greater Love () | £796 | £2,694 | £18,830 | -65% | 5 |
| 26 (new) |  | Cameraman: The Life and Work of Jack Cardiff () | £669 | £669 | £669 | new | 1 |
| 27 (29) |  | Exit Through the Gift Shop (2010) | £449 | £3,305 | £311,486 | -41% | 10 |
| 28 (24) |  | Cherrybomb () | £325 | £1,632 | £15,796 | -81% | 3 |
| 29 (19) | | Perriers Bounty () | £308 | £3,767 | £342,957 | -91% | 7 |
| 30 (21) |  | An Education () | £20 | £1,328 | £2,584,736 | -99% | 26 |