| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Clash of the Titans (2010) | £2,441,682 | £6,973,160 | £12,656,035 | -57% | 2 |
| 2 (2) |  | How to Train Your Dragon (2010) | £1,399,017 | £4,936,261 | £9,782,793 | -71% | 2 |
| 3 (3) |  | Kick-Ass (2010) | £1,191,069 | £3,119,376 | £7,001,080 | -69% | 2 |
| 4 (4) |  | Nanny Mcphee and the Big Bang (2010) | £1,180,193 | £4,754,120 | £11,906,088 | -55% | 3 |
| 5 (5) |  | Alice In Wonderland (2010) | £676,516 | £2,143,770 | £40,083,901 | -47% | 6 |
| 6 (6) |  | The Blind Side (2010) | £538,730 | £1,500,033 | £4,903,322 | -46% | 3 |
| 7 (7) |  | Remember Me (2010) | £521,757 | £1,652,575 | £2,639,885 | -47% | 2 |
| 8 (new) |  | Whip It (2010) | £353,041 | £353,041 | £353,041 | new | 1 |
| 9 (8) |  | Shutter Island (2010) | £336,725 | £878,594 | £10,038,604 | -52% | 5 |
| 10 (9) |  | The Bounty Hunter (2010) | £222,664 | £707,758 | £5,851,965 | -56% | 4 |
| 11 (new) | | Io Sono L'amore (2010) | £171,959 | £171,959 | £171,959 | new | 1 |
| 12 (new) |  | Shelter (2010) | £141,452 | £141,452 | £141,452 | new | 1 |
| 13 (10) |  | The Spy Next Door (2010) | £137,485 | £529,913 | £2,305,597 | -46% | 4 |
| 14 (new) | | The Infidel (2010) | £135,448 | £135,448 | £135,448 | new | 1 |
| 15 (new) | | Prince (2010) | £68,277 | £68,277 | £68,277 | new | 1 |
| 16 (16) | | Perriers Bounty (2010) | £19,256 | £59,079 | £289,430 | -56% | 3 |
| 17 (20) |  | Planet 51 (2009) | £7,943 | £9,303 | £5,013,655 | -31% | 18 |
| 18 (22) |  | An Education (2009) | £3,209 | £35,774 | £2,520,214 | -45% | 22 |
| 19 (21) |  | Exit Through the Gift Shop (2010) | £3,070 | £11,586 | £293,263 | -69% | 6 |
| 20 (new) |  | No Greater Love (2010) | £2,453 | £2,453 | £2,453 | new | 1 |
| 21 (26) |  | Nine (2009) | £1,000 | £2,288 | £3,280,616 | 14% | 16 |
| 22 (28) | | Sons of Cuba (2009) | £815 | £2,437 | £6,517 | 73% | 4 |
| 23 (31) | | Mugabe and the White African (2010) | £407 | £2,554 | £78,819 | 95% | 13 |
| 24 (24) |  | The Wolfman (2010) | £302 | £1,310 | £5,006,719 | -78% | 8 |
| 25 (new) | | I Know You Know (2010) | £240 | £240 | £240 | new | 1 |
| 26 (27) |  | Sex & Drugs & Rock & Roll (2010) | £179 | £3,260 | £880,219 | -73% | 13 |
| 27 (32) | | She, a Chinese (2009) | £20 | £105 | £11,353 | 0% | 7 |