| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Clash of the Titans () | £5,682,875 | £5,682,875 | £5,682,875 | new | 1 |
| 2 (new) |  | How to Train Your Dragon (2010) | £4,846,532 | £4,846,532 | £4,846,532 | new | 1 |
| 3 (new) |  | Kick-Ass () | £3,881,704 | £3,881,704 | £3,881,704 | new | 1 |
| 4 (1) |  | Nanny Mcphee and the Big Bang (2010) | £2,600,678 | £4,565,208 | £7,151,968 | 1% | 2 |
| 5 (2) |  | Alice In Wonderland () | £1,285,889 | £3,122,343 | £37,940,131 | -48% | 5 |
| 6 (3) |  | The Blind Side () | £1,003,855 | £2,089,972 | £3,403,289 | -24% | 2 |
| 7 (new) |  | Remember Me (2010) | £987,310 | £987,310 | £987,310 | new | 1 |
| 8 (4) |  | Shutter Island (2010) | £705,499 | £1,482,755 | £9,160,010 | -38% | 4 |
| 9 (5) |  | The Bounty Hunter (2010) | £510,237 | £1,234,552 | £5,144,207 | -49% | 3 |
| 10 (7) |  | The Spy Next Door () | £256,892 | £540,190 | £1,775,684 | -35% | 3 |
| 11 (6) |  | Green Zone () | £170,503 | £478,085 | £5,429,903 | -63% | 4 |
| 12 (11) |  | The Girl With the Dragon Tattoo () | £117,726 | £251,892 | £1,540,009 | -28% | 4 |
| 13 (8) |  | I Love You Phillip Morris () | £112,738 | £391,567 | £2,298,494 | -69% | 3 |
| 14 (10) |  | Avatar () | £107,629 | £301,116 | £91,354,118 | -52% | 16 |
| 15 (re) |  | Shank () | £68,888 | £68,888 | £469,213 | re | 2 |
| 16 (12) | | Perriers Bounty () | £44,122 | £122,699 | £230,351 | -59% | 2 |
| 17 (new) |  | Samson & Delilah () | £30,170 | £30,170 | £30,170 | new | 1 |
| 18 (new) | | Sadiyaan () | £29,009 | £29,009 | £29,009 | new | 1 |
| 19 (new) | | Paiyaa () | £21,021 | £21,021 | £21,021 | new | 1 |
| 20 (18) |  | Planet 51 () | £11,429 | £11,663 | £5,004,352 | 30% | 17 |
| 21 (17) |  | Exit Through the Gift Shop (2010) | £9,821 | £22,367 | £281,677 | -19% | 5 |
| 22 (22) |  | An Education () | £5,861 | £11,739 | £2,484,440 | 13% | 21 |
| 23 (new) | | Double Take (2010) | £3,515 | £3,515 | £3,515 | new | 1 |
| 24 (27) |  | The Wolfman () | £1,403 | £4,686 | £5,005,409 | -50% | 7 |
| 25 (26) |  | The Scouting Book For Boys (2009) | £940 | £3,474 | £27,404 | -71% | 3 |
| 26 (34) |  | Nine (2009) | £857 | £1,001 | £3,278,328 | 61% | 15 |
| 27 (32) |  | Sex & Drugs & Rock & Roll () | £653 | £3,245 | £876,959 | 15% | 12 |
| 28 (31) | | Sons of Cuba (2009) | £223 | £1,289 | £4,080 | -72% | 3 |
| 29 (new) |  | City of War () | £145 | £145 | £145 | new | 1 |
| 30 (35) |  | 44 Inch Chest (2010) | £20 | £505 | £403,543 | -84% | 11 |
| 31 (33) | | Mugabe and the White African () | £20 | £20 | £76,265 | -95% | 12 |
| 32 (36) | | She, a Chinese (2009) | £20 | £20 | £11,248 | -64% | 6 |