| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Avatar () | £4,338,774 | £6,865,793 | £71,936,392 | -11% | 8 |
| 2 (new) |  | The Princess and the Frog () | £2,239,759 | £2,224,108 | £2,239,759 | 99% | 2 |
| 3 (new) |  | Astro Boy (2009) | £1,091,872 | £1,091,872 | £1,091,872 | new | 1 |
| 4 (new) |  | Invictus () | £1,068,388 | £1,068,388 | £1,068,388 | new | 1 |
| 5 (4) |  | Sherlock Holmes () | £783,681 | £1,296,296 | £24,474,393 | -32% | 7 |
| 6 (3) |  | Edge of Darkness () | £768,013 | £1,478,351 | £2,651,278 | -35% | 2 |
| 7 (new) |  | Youth In Revolt () | £743,932 | £743,932 | £743,932 | new | 1 |
| 8 (2) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £729,683 | £883,837 | £20,837,031 | -39% | 7 |
| 9 (5) |  | Its Complicated () | £560,573 | £1,195,627 | £8,288,948 | -34% | 5 |
| 10 (6) |  | Up In the Air (2009) | £481,810 | £945,658 | £5,580,729 | -34% | 4 |
| 11 (9) |  | Precious: Based On the Novel Push By Sapphire () | £369,295 | £551,870 | £812,791 | 29% | 2 |
| 12 (8) |  | The Book of Eli (2010) | £225,850 | £495,781 | £4,017,681 | -53% | 4 |
| 13 (12) | | A Prophet () | £126,606 | £270,983 | £960,306 | -38% | 3 |
| 14 (10) |  | Daybreakers (2009) | £84,483 | £221,057 | £4,185,646 | -65% | 5 |
| 15 (11) |  | Brother's (2010) | £83,156 | £232,589 | £1,028,334 | -60% | 3 |
| 16 (14) |  | St. Trinian's 2: The Legend of Frittons Gold (2009) | £65,032 | £76,728 | £7,019,714 | -52% | 8 |
| 17 (new) |  | Asal (2010) | £38,809 | £38,809 | £38,809 | new | 1 |
| 18 (16) |  | Sex & Drugs & Rock & Roll () | £33,783 | £84,632 | £747,644 | -47% | 5 |
| 19 (20) |  | An Education () | £29,552 | £73,904 | £2,164,253 | -13% | 14 |
| 20 (19) |  | Nine (2009) | £24,485 | £70,132 | £3,167,562 | -42% | 8 |
| 21 (17) |  | Planet 51 () | £24,271 | £27,386 | £4,696,283 | -56% | 10 |
| 22 (24) |  | Fantastic Mr. Fox () | £11,527 | £12,471 | £8,995,456 | -17% | 15 |
| 23 (22) |  | Nowhere Boy () | £10,005 | £39,865 | £1,244,722 | -58% | 7 |
| 24 (28) | | Mugabe and the White African () | £4,503 | £7,025 | £41,189 | 54% | 5 |
| 25 (new) |  | Holy Water () | £4,499 | £4,499 | £4,499 | new | 1 |
| 26 (21) |  | 44 Inch Chest (2010) | £3,556 | £26,480 | £395,203 | -89% | 4 |
| 27 (new) | | Tony (2010) | £2,102 | £2,102 | £2,102 | new | 1 |
| 28 (32) | | Me and Orson Welles (2008) | £1,424 | £1,962 | £451,957 | 56% | 9 |
| 29 (new) | | Oil City Confidential () | £1,272 | £1,272 | £1,272 | new | 1 |
| 30 (25) |  | The Boys Are Back () | £608 | £9,593 | £124,364 | -95% | 3 |
| 31 (33) |  | Nativity! () | £355 | £8,337 | £5,187,192 | -27% | 11 |
| 32 (27) |  | Glorious 39 (2009) | £315 | £6,627 | £288,556 | -90% | 11 |
| 33 (29) | | Bright Star () | £236 | £3,982 | £1,057,002 | -88% | 13 |
| 34 (37) |  | Harry Brown (2009) | £220 | £1,320 | £4,555,407 | 86% | 12 |
| 35 (35) |  | Bunny and the Bull (2009) | £100 | £796 | £87,590 | -62% | 10 |
| 36 (36) | | Cracks () | £20 | £630 | £104,460 | -92% | 9 |