| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Avatar () | £5,527,039 | £8,382,719 | £49,374,516 | 14% | 5 |
| 2 (2) |  | Sherlock Holmes () | £2,028,282 | £3,152,568 | £18,829,133 | 0% | 4 |
| 3 (4) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £1,542,970 | £1,856,076 | £16,862,702 | 21% | 4 |
| 4 (5) |  | Its Complicated () | £1,300,580 | £2,192,598 | £3,291,257 | 16% | 2 |
| 5 (new) |  | Up In the Air (2009) | £1,298,023 | £1,298,023 | £1,298,023 | new | 1 |
| 6 (new) |  | The Book of Eli (2010) | £1,232,001 | £1,232,001 | £1,232,001 | new | 1 |
| 7 (3) |  | Daybreakers (2009) | £804,762 | £1,392,787 | £2,737,375 | -40% | 2 |
| 8 (6) |  | The Road (2010) | £470,652 | £882,828 | £1,509,975 | -25% | 2 |
| 9 (7) |  | Did You Hear About the Morgans? () | £396,106 | £718,861 | £2,966,211 | -29% | 3 |
| 10 (9) |  | St. Trinian's 2: The Legend of Frittons Gold (2009) | £282,047 | £363,743 | £6,545,874 | -4% | 5 |
| 11 (new) |  | All About Steve (2010) | £275,083 | £275,083 | £275,083 | new | 1 |
| 12 (new) |  | 44 Inch Chest (2010) | £152,171 | £152,171 | £152,171 | new | 1 |
| 13 (8) |  | Nine (2009) | £149,594 | £409,128 | £2,811,110 | -56% | 5 |
| 14 (10) |  | Sex & Drugs & Rock & Roll () | £133,773 | £254,125 | £427,956 | -23% | 2 |
| 15 (11) |  | 3 Idiots (2009) | £119,450 | £186,532 | £1,556,346 | -15% | 4 |
| 16 (13) |  | Planet 51 () | £90,578 | £100,766 | £4,529,680 | 13% | 7 |
| 17 (new) | | Chance Pe Dance (2010) | £72,921 | £72,921 | £72,921 | new | 1 |
| 18 (14) |  | Nowhere Boy () | £44,472 | £109,478 | £1,078,449 | -42% | 4 |
| 19 (new) | | Ayirathil Oruvan () | £29,517 | £29,517 | £29,517 | new | 1 |
| 20 (18) |  | Fantastic Mr. Fox () | £23,602 | £27,279 | £8,946,626 | 48% | 12 |
| 21 (new) |  | Still Walking (2008) | £11,808 | £11,808 | £11,808 | new | 1 |
| 22 (19) |  | An Education () | £6,234 | £17,113 | £1,997,842 | -8% | 11 |
| 23 (20) | | Mugabe and the White African () | £5,339 | £10,525 | £15,995 | -2% | 2 |
| 24 (new) |  | OSS 117: Lost In Rio () | £4,845 | £4,845 | £4,845 | new | 1 |
| 25 (22) | | Bright Star () | £3,836 | £9,765 | £1,038,896 | -10% | 10 |
| 26 (23) |  | Glorious 39 (2009) | £3,294 | £9,567 | £263,377 | -14% | 8 |
| 27 (24) |  | Harry Brown (2009) | £2,998 | £4,718 | £4,548,727 | -8% | 9 |
| 28 (17) |  | Nativity! () | £2,672 | £3,679 | £5,176,563 | -80% | 8 |
| 29 (29) |  | The Imaginarium of Doctor Parnassus () | £2,613 | £3,148 | £3,926,632 | 53% | 13 |
| 30 (27) | | Me and Orson Welles (2008) | £2,194 | £4,287 | £438,587 | -4% | 6 |
| 31 (new) | | Crude () | £1,879 | £1,879 | £1,879 | new | 1 |
| 32 (28) | | Cracks () | £1,226 | £4,150 | £100,767 | -4% | 6 |
| 33 (26) |  | Exam () | £834 | £2,678 | £5,521 | -71% | 2 |
| 34 (33) |  | Bunny and the Bull (2009) | £149 | £451 | £84,216 | 87% | 7 |