| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Avatar (2009) | £4,770,980 | £8,176,179 | £40,991,797 | -20% | 4 |
| 2 (2) |  | Sherlock Holmes (2009) | £2,026,732 | £3,654,835 | £15,676,565 | -41% | 3 |
| 3 (new) |  | Daybreakers (2009) | £1,344,588 | £1,344,588 | £1,344,588 | new | 1 |
| 4 (3) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £1,220,271 | £2,412,216 | £15,006,626 | -50% | 3 |
| 5 (new) |  | Its Complicated (2009) | £1,098,659 | £1,098,659 | £1,098,659 | new | 1 |
| 6 (new) |  | The Road (2010) | £627,147 | £627,147 | £627,147 | new | 1 |
| 7 (4) |  | Did You Hear About the Morgans? (2010) | £558,415 | £1,092,290 | £2,247,350 | -52% | 2 |
| 8 (5) |  | Nine (2009) | £338,454 | £748,435 | £2,401,982 | -57% | 4 |
| 9 (6) |  | St. Trinian's 2: The Legend of Frittons Gold (2009) | £293,904 | £606,344 | £6,182,131 | -56% | 4 |
| 10 (new) |  | Sex & Drugs & Rock & Roll (2010) | £173,831 | £173,831 | £173,831 | new | 1 |
| 11 (7) |  | 3 Idiots (2009) | £140,248 | £254,284 | £1,369,814 | -58% | 3 |
| 12 (9) |  | The Twilight Saga: New Moon (2009) | £95,613 | £195,063 | £27,083,155 | -56% | 8 |
| 13 (10) |  | Planet 51 (2009) | £79,190 | £151,677 | £4,428,914 | -52% | 6 |
| 14 (8) |  | Nowhere Boy (2009) | £77,101 | £219,918 | £968,971 | -67% | 3 |
| 15 (new) |  | I Found a Groom (2010) | £71,760 | £71,760 | £71,760 | new | 1 |
| 16 (new) |  | Pyaar Impossible (2010) | £16,207 | £16,207 | £16,207 | new | 1 |
| 17 (14) |  | Nativity! (2009) | £13,174 | £48,682 | £5,172,884 | -86% | 7 |
| 18 (16) |  | Fantastic Mr. Fox (2009) | £12,275 | £23,498 | £8,919,347 | -72% | 11 |
| 19 (19) |  | An Education (2009) | £6,777 | £17,252 | £1,980,729 | -25% | 10 |
| 20 (new) | | Mugabe and the White African (2010) | £5,470 | £5,470 | £5,470 | new | 1 |
| 21 (new) | | Treeless Mountain (2009) | £4,374 | £4,374 | £4,374 | new | 1 |
| 22 (20) | | Bright Star (2009) | £4,280 | £7,971 | £1,029,131 | -19% | 9 |
| 23 (24) |  | Glorious 39 (2009) | £3,815 | £9,369 | £253,810 | 28% | 7 |
| 24 (23) |  | Harry Brown (2009) | £3,256 | £5,394 | £4,544,009 | -1% | 8 |
| 25 (new) |  | Mitti (2010) | £3,090 | £3,090 | £3,090 | new | 1 |
| 26 (new) |  | Exam (2010) | £2,843 | £2,843 | £2,843 | new | 1 |
| 27 (22) | | Me and Orson Welles (2008) | £2,292 | £7,800 | £434,300 | -41% | 5 |
| 28 (27) | | Cracks (2009) | £1,271 | £3,203 | £96,617 | 48% | 5 |
| 29 (26) |  | The Imaginarium of Doctor Parnassus (2009) | £1,233 | £2,641 | £3,923,484 | -8% | 12 |
| 30 (new) | | Fireball (2010) | £392 | £392 | £392 | new | 1 |
| 31 (30) | | Fish Tank (2009) | £323 | £1,310 | £598,162 | 94% | 16 |
| 32 (25) |  | The Descent Part 2 (2009) | £66 | £249 | £674,550 | -95% | 5 |
| 33 (29) |  | Bunny and the Bull (2009) | £20 | £717 | £83,765 | -87% | 6 |