| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Avatar () | £4,770,980 | £8,176,179 | £40,991,797 | -20% | 4 |
| 2 (2) |  | Sherlock Holmes () | £2,026,732 | £3,654,835 | £15,676,565 | -41% | 3 |
| 3 (new) |  | Daybreakers (2009) | £1,344,588 | £1,344,588 | £1,344,588 | new | 1 |
| 4 (3) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £1,220,271 | £2,412,216 | £15,006,626 | -50% | 3 |
| 5 (new) |  | Its Complicated () | £1,098,659 | £1,098,659 | £1,098,659 | new | 1 |
| 6 (new) |  | The Road (2010) | £627,147 | £627,147 | £627,147 | new | 1 |
| 7 (4) |  | Did You Hear About the Morgans? () | £558,415 | £1,092,290 | £2,247,350 | -52% | 2 |
| 8 (5) |  | Nine (2009) | £338,454 | £748,435 | £2,401,982 | -57% | 4 |
| 9 (6) |  | St. Trinian's 2: The Legend of Frittons Gold (2009) | £293,904 | £606,344 | £6,182,131 | -56% | 4 |
| 10 (new) |  | Sex & Drugs & Rock & Roll () | £173,831 | £173,831 | £173,831 | new | 1 |
| 11 (7) |  | 3 Idiots (2009) | £140,248 | £254,284 | £1,369,814 | -58% | 3 |
| 12 (9) |  | The Twilight Saga: New Moon () | £95,613 | £195,063 | £27,083,155 | -56% | 8 |
| 13 (10) |  | Planet 51 () | £79,190 | £151,677 | £4,428,914 | -52% | 6 |
| 14 (8) |  | Nowhere Boy () | £77,101 | £219,918 | £968,971 | -67% | 3 |
| 15 (new) |  | I Found a Groom () | £71,760 | £71,760 | £71,760 | new | 1 |