| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Harry Potter and the Half Blood Prince () | £19,784,924 | £19,784,924 | £19,784,924 | new | 1 |
| 2 (2) |  | Ice Age: Dawn of the Dinosaurs () | £2,849,981 | £4,879,167 | £20,300,698 | -40% | 3 |
| 3 (1) |  | Brüno (2009) | £2,301,432 | £5,357,266 | £10,357,495 | -54% | 2 |
| 4 (4) |  | The Hangover (2009) | £881,514 | £1,648,122 | £18,142,083 | -28% | 6 |
| 5 (3) |  | Transformers: Revenge of the Fallen () | £678,743 | £1,339,814 | £24,919,977 | -53% | 5 |
| 6 (5) |  | Public Enemies () | £470,651 | £1,118,843 | £5,728,410 | -55% | 3 |
| 7 (6) |  | My Sisters Keeper () | £378,680 | £879,704 | £4,955,541 | -44% | 4 |
| 8 (new) |  | Moon (2009) | £157,867 | £157,867 | £157,867 | new | 1 |
| 9 (7) |  | Year One (2009) | £53,033 | £138,880 | £2,776,236 | -78% | 4 |
| 10 (8) |  | Night At the Museum 2 (2009) | £49,570 | £85,132 | £19,560,553 | -53% | 9 |
| 11 (9) | | Kambakkht Ishq () | £33,601 | £86,408 | £637,702 | -68% | 3 |
| 12 (new) | | Burma Vj Reporter I Et Lukket Land (2008) | £31,522 | £31,522 | £31,522 | new | 1 |
| 13 (16) | | 35 Shots of Rum (2009) | £30,521 | £51,440 | £78,375 | 12% | 2 |
| 14 (10) | | Short Kut: The Con Is On () | £23,901 | £63,438 | £143,926 | -70% | 2 |
| 15 (new) | | Frozen River (2009) | £18,594 | £18,594 | £18,594 | new | 1 |
| 16 (15) |  | Looking For Eric () | £12,266 | £36,170 | £1,219,640 | -54% | 6 |
| 17 (new) |  | The Informers (2009) | £6,149 | £6,149 | £6,149 | new | 1 |
| 18 (new) |  | Wide Open Spaces (2009) | £5,924 | £5,924 | £5,924 | new | 1 |
| 19 (17) | | Last Chance Harvey (2008) | £4,781 | £17,108 | £2,013,762 | -50% | 7 |
| 20 (new) | | Kisses (2008) | £4,001 | £4,001 | £4,001 | new | 2 |
| 21 (20) |  | In the Loop (2009) | £719 | £3,631 | £2,139,673 | -57% | 14 |
| 22 (24) | | The End of the Line () | £661 | £1,467 | £51,479 | 5% | 6 |
| 23 (21) |  | Sugar (2009) | £552 | £2,469 | £27,974 | -61% | 6 |
| 24 (23) |  | Telstar () | £457 | £2,391 | £59,113 | -55% | 5 |
| 25 (22) |  | Chéri (2009) | £426 | £2,891 | £412,130 | -62% | 11 |
| 26 (re) |  | Is Anybody There? () | £312 | £312 | £461,909 | re | 10 |
| 27 (re) | | New Town Killers (2009) | £303 | £303 | £6,599 | re | 5 |
| 28 (re) |  | The Young Victoria (2009) | £220 | £220 | £4,950,745 | re | 17 |