| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Madagascar Escape 2 Africa () | £6,342,997 | £6,342,997 | £6,342,997 | new | 1 |
| 2 (1) |  | Four Christmases () | £1,498,592 | £2,438,284 | £4,713,869 | -34% | 2 |
| 3 (new) |  | Transporter 3 () | £958,615 | £958,615 | £958,615 | new | 1 |
| 4 (3) |  | Changeling (2008) | £721,221 | £1,439,357 | £2,664,905 | -41% | 2 |
| 5 (2) |  | Quantum of Solace () | £720,390 | £1,292,298 | £48,955,117 | -50% | 6 |
| 6 (4) |  | Body of Lies (2008) | £260,503 | £540,609 | £2,554,760 | -50% | 3 |
| 7 (new) |  | Lakeview Terrace () | £224,493 | £224,493 | £224,493 | new | 1 |
| 8 (5) |  | My Best Friends Girl (2008) | £125,690 | £317,780 | £1,932,503 | -61% | 3 |
| 9 (6) |  | High School Musical 3: Senior Year () | £110,110 | £161,482 | £22,569,628 | -61% | 7 |
| 10 (new) |  | The Children () | £98,205 | £98,205 | £98,205 | new | 1 |
| 11 (8) |  | Zack and Miri Make a Porno () | £83,090 | £210,980 | £2,373,557 | -53% | 4 |
| 12 (new) |  | The Secret Life of Bees (2008) | £74,626 | £74,626 | £74,626 | new | 1 |
| 13 (7) |  | What Just Happened () | £56,258 | £169,413 | £348,231 | -69% | 2 |
| 14 (13) |  | Waltz With Bashir (2008) | £50,218 | £117,430 | £406,090 | -46% | 3 |
| 15 (9) |  | Quarantine (2008) | £48,747 | £162,754 | £937,833 | -70% | 3 |
| 16 (new) | | Julia () | £18,828 | £18,828 | £18,828 | new | 1 |
| 17 (18) |  | Hunger () | £14,484 | £30,949 | £754,018 | -23% | 6 |
| 18 (new) | | Summer () | £13,271 | £13,271 | £13,271 | new | 1 |
| 19 (19) |  | Mamma Mia! () | £9,922 | £71,259 | £68,735,783 | -46% | 22 |
| 20 (new) | | Rivals (2008) | £7,919 | £7,919 | £7,919 | new | 1 |
| 21 (22) |  | The Boy In the Striped Pajamas () | £5,986 | £14,506 | £4,470,326 | -26% | 13 |
| 22 (new) |  | The Express (2008) | £5,355 | £5,355 | £5,355 | new | 1 |
| 23 (17) |  | The Dark Knight () | £3,376 | £20,300 | £48,676,047 | -84% | 20 |
| 24 (new) |  | Gumnaam the Mystery () | £2,368 | £2,368 | £2,368 | new | 1 |
| 25 (25) |  | The Duchess () | £2,304 | £5,637 | £7,066,550 | -30% | 14 |
| 26 (24) |  | Of Time and the City () | £1,754 | £8,168 | £224,779 | -70% | 6 |
| 27 (new) | | Caught In the Act (2008) | £1,231 | £1,231 | £1,231 | new | 1 |
| 28 (27) |  | City of Ember () | £865 | £1,331 | £1,413,838 | -21% | 9 |
| 29 (new) | | The Girl In the Park (2008) | £764 | £764 | £764 | new | 1 |
| 30 (20) | | Flawless (2008) | £557 | £11,968 | £26,677 | -96% | 2 |
| 31 (new) |  | The Lost City (2008) | £382 | £382 | £382 | new | 1 |