| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Four Christmases () | £2,275,585 | £2,275,585 | £2,275,585 | new | 1 |
| 2 (1) |  | Quantum of Solace () | £1,453,184 | £2,542,795 | £47,662,819 | -50% | 5 |
| 3 (new) |  | Changeling (2008) | £1,225,548 | £1,225,548 | £1,225,548 | new | 1 |
| 4 (2) |  | Body of Lies (2008) | £518,990 | £1,022,172 | £2,014,151 | -48% | 2 |
| 5 (3) |  | My Best Friends Girl (2008) | £326,064 | £703,368 | £1,614,723 | -64% | 2 |
| 6 (4) |  | High School Musical 3: Senior Year () | £280,482 | £372,174 | £22,408,146 | -54% | 6 |
| 7 (new) |  | What Just Happened () | £178,818 | £178,818 | £178,818 | new | 1 |
| 8 (5) |  | Zack and Miri Make a Porno () | £178,256 | £405,781 | £2,162,577 | -60% | 3 |
| 9 (8) |  | Quarantine (2008) | £160,333 | £387,085 | £775,079 | -59% | 2 |
| 10 (6) |  | Max Payne () | £132,888 | £325,569 | £2,268,901 | -69% | 3 |
| 11 (7) |  | Ghost Town (2008) | £131,356 | £246,388 | £6,370,608 | -67% | 6 |
| 12 (10) |  | Dostana () | £95,254 | £160,761 | £842,424 | -47% | 2 |
| 13 (12) |  | Waltz With Bashir (2008) | £92,300 | £175,573 | £288,660 | -18% | 2 |
| 14 (11) |  | Burn After Reading (2008) | £55,112 | £108,953 | £7,595,968 | -52% | 7 |
| 15 (re) |  | The Baader Meinhof Complex () | £30,918 | £30,918 | £307,013 | re | 2 |
| 16 (new) | | Niko and the Way to the Stars () | £24,599 | £24,599 | £24,599 | new | 1 |
| 17 (20) |  | The Dark Knight () | £21,707 | £23,589 | £48,655,747 | -3% | 19 |
| 18 (17) |  | Hunger () | £18,796 | £52,428 | £723,069 | -57% | 5 |
| 19 (14) |  | Mamma Mia! () | £18,264 | £548,432 | £68,664,524 | -79% | 21 |
| 20 (new) | | Flawless (2008) | £14,709 | £14,709 | £14,709 | new | 1 |
| 21 (new) | | Oye Lucky Lucky Oye () | £14,709 | £14,709 | £14,709 | new | 1 |
| 22 (19) |  | The Boy In the Striped Pajamas () | £8,138 | £30,919 | £4,455,820 | -67% | 12 |
| 23 (new) | | The Silence of Lorna () | £7,047 | £7,047 | £7,047 | new | 1 |
| 24 (22) |  | Of Time and the City () | £5,827 | £12,238 | £216,611 | -19% | 5 |
| 25 (25) |  | The Duchess () | £3,271 | £33,663 | £7,060,913 | -16% | 13 |
| 26 (new) | | Ano Una () | £3,177 | £3,177 | £3,177 | new | 1 |
| 27 (23) |  | City of Ember () | £1,098 | £1,599 | £1,412,507 | -81% | 8 |
| 28 (28) | | The Fall () | £983 | £983 | £79,276 | 44% | 7 |
| 29 (31) | | Unrelated () | £477 | £1,022 | £100,426 | 61% | 9 |
| 30 (27) |  | How to Lose Friends and Alienate People (2008) | £433 | £1,707 | £4,086,924 | -48% | 9 |