| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Quantum of Solace () | £2,884,789 | £4,839,217 | £45,120,024 | -44% | 4 |
| 2 (new) |  | Body of Lies (2008) | £991,979 | £991,979 | £991,979 | new | 1 |
| 3 (new) |  | My Best Friends Girl (2008) | £911,355 | £911,355 | £911,355 | new | 1 |
| 4 (3) |  | High School Musical 3: Senior Year () | £608,193 | £792,456 | £22,035,972 | -38% | 5 |
| 5 (4) |  | Zack and Miri Make a Porno () | £447,485 | £958,591 | £1,756,796 | -44% | 2 |
| 6 (2) |  | Max Payne () | £434,992 | £938,337 | £1,943,332 | -57% | 2 |
| 7 (5) |  | Ghost Town (2008) | £392,822 | £628,786 | £6,124,220 | -34% | 5 |
| 8 (new) |  | Quarantine (2008) | £387,994 | £387,994 | £387,994 | new | 1 |
| 9 (9) |  | Igor () | £178,717 | £194,754 | £3,677,369 | -19% | 6 |
| 10 (re) |  | Dostana () | £178,663 | £178,663 | £681,663 | re | 1 |
| 11 (7) |  | Burn After Reading (2008) | £114,354 | £249,621 | £7,487,015 | -55% | 6 |
| 12 (new) |  | Waltz With Bashir (2008) | £113,087 | £113,087 | £113,087 | new | 1 |
| 13 (new) |  | Yuvvraaj (2008) | £112,688 | £112,688 | £112,688 | new | 1 |
| 14 (13) |  | Mamma Mia! () | £87,646 | £236,653 | £68,116,092 | -42% | 20 |
| 15 (8) |  | Easy Virtue () | £81,755 | £255,596 | £1,130,043 | -64% | 3 |
| 16 (new) |  | Choke (2008) | £59,330 | £59,330 | £59,330 | new | 1 |
| 17 (15) |  | Hunger () | £43,857 | £109,507 | £670,641 | -53% | 4 |
| 18 (new) | | Kisses (2008) | £37,102 | £37,102 | £37,102 | new | 1 |
| 19 (17) |  | The Boy In the Striped Pajamas () | £24,651 | £86,930 | £4,424,901 | -24% | 11 |
| 20 (23) |  | The Dark Knight () | £22,296 | £25,811 | £48,632,158 | 80% | 18 |
| 21 (re) |  | Blindness () | £8,609 | £8,609 | £38,609 | re | 1 |
| 22 (18) |  | Of Time and the City () | £7,177 | £24,518 | £204,373 | -63% | 4 |
| 23 (19) |  | City of Ember () | £5,744 | £6,193 | £1,410,908 | -45% | 7 |
| 24 (new) | | Conversations With My Gardener () | £4,357 | £4,357 | £4,357 | new | 1 |
| 25 (20) |  | The Duchess () | £3,914 | £9,854 | £7,027,250 | -52% | 12 |
| 26 (new) | | Belle Toujours () | £1,136 | £1,136 | £1,136 | new | 1 |
| 27 (21) |  | How to Lose Friends and Alienate People (2008) | £825 | £5,264 | £4,085,217 | -87% | 8 |
| 28 (28) | | The Fall () | £554 | £2,815 | £78,293 | 58% | 6 |
| 29 (25) |  | Man On Wire () | £547 | £4,253 | £868,656 | -63% | 17 |
| 30 (new) | | Special People () | £480 | £480 | £480 | new | 1 |
| 31 (re) | | Unrelated () | £187 | £187 | £99,404 | re | 8 |
| 32 (27) |  | Somers Town () | £20 | £1,348 | £566,616 | -96% | 13 |
| 33 (re) |  | Miss Pettigrew Lives For a Day (2008) | £20 | £20 | £457,549 | re | 11 |