| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | High School Musical 3: Senior Year () | £8,409,375 | £8,409,375 | £8,409,375 | new | 1 |
| 2 (new) |  | Saw V (2008) | £2,436,817 | £2,436,817 | £2,436,817 | new | 1 |
| 3 (1) |  | Burn After Reading (2008) | £1,433,536 | £2,544,195 | £4,589,760 | -30% | 2 |
| 4 (new) |  | Ghost Town (2008) | £1,347,678 | £1,347,678 | £1,347,678 | new | 1 |
| 5 (2) |  | Eagle Eye () | £695,611 | £1,250,292 | £2,347,069 | -37% | 2 |
| 6 (3) |  | Igor () | £451,742 | £641,280 | £1,752,139 | -54% | 2 |
| 7 (4) |  | The House Bunny () | £305,197 | £535,108 | £2,506,846 | -54% | 3 |
| 8 (6) |  | Taken (2008) | £260,342 | £521,535 | £6,046,921 | -51% | 5 |
| 9 (8) |  | Mamma Mia! () | £257,705 | £895,408 | £66,827,983 | -40% | 16 |
| 10 (5) |  | Mirrors () | £226,326 | £484,736 | £2,403,301 | -61% | 3 |
| 11 (7) |  | How to Lose Friends and Alienate People (2008) | £162,790 | £376,558 | £3,927,139 | -63% | 4 |
| 12 (12) |  | The Boy In the Striped Pajamas () | £110,790 | £235,358 | £3,975,047 | -44% | 7 |
| 13 (new) | | Heroes () | £107,090 | £107,090 | £107,090 | new | 1 |
| 14 (9) |  | City of Ember () | £102,429 | £177,975 | £1,147,808 | -64% | 3 |
| 15 (13) |  | Gomorrah (2008) | £91,320 | £178,907 | £620,717 | -33% | 3 |
| 16 (16) |  | Brideshead Revisited (2008) | £35,393 | £97,629 | £1,236,438 | -51% | 4 |
| 17 (new) |  | Roadside Romeo (2008) | £31,620 | £31,620 | £31,620 | new | 1 |
| 18 (18) |  | The Duchess () | £23,606 | £115,629 | £6,872,962 | -33% | 8 |
| 19 (new) | | Quiet Chaos (2008) | £22,485 | £22,485 | £22,485 | new | 1 |
| 20 (new) | | Aegan () | £22,165 | £22,165 | £22,165 | new | 1 |
| 21 (new) |  | Incendiary () | £18,964 | £18,964 | £18,964 | new | 1 |
| 22 (21) |  | The Dark Knight () | £16,540 | £25,337 | £48,527,574 | -11% | 14 |
| 23 (19) |  | Stone of Destiny (2008) | £6,193 | £20,169 | £143,695 | -78% | 3 |
| 24 (25) | | Unrelated () | £2,798 | £8,536 | £87,238 | -48% | 6 |
| 25 (re) | | The Fall () | £1,732 | £1,732 | £65,835 | re | 2 |
| 26 (re) |  | Somers Town () | £1,665 | £1,665 | £557,566 | re | 9 |
| 27 (22) |  | Wild Child () | £1,638 | £2,804 | £5,122,425 | -84% | 11 |
| 28 (new) | | Outlanders (2008) | £1,513 | £1,513 | £1,513 | new | 1 |
| 29 (28) |  | Man On Wire () | £664 | £2,894 | £851,947 | -54% | 13 |
| 30 (re) |  | Miss Pettigrew Lives For a Day (2008) | £662 | £662 | £441,457 | re | 9 |
| 31 (new) | | A Bloody Aria (2008) | £629 | £629 | £629 | new | 1 |
| 32 (re) |  | The Edge of Love (2008) | £20 | £20 | £1,506,394 | re | 15 |