| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | High School Musical 3: Senior Year () | £8,409,375 | £8,409,375 | £8,409,375 | new | 1 |
| 2 (new) |  | Saw V (2008) | £2,436,817 | £2,436,817 | £2,436,817 | new | 1 |
| 3 (1) |  | Burn After Reading (2008) | £1,433,536 | £2,544,195 | £4,589,760 | -30% | 2 |
| 4 (new) |  | Ghost Town (2008) | £1,347,678 | £1,347,678 | £1,347,678 | new | 1 |
| 5 (2) |  | Eagle Eye () | £695,611 | £1,250,292 | £2,347,069 | -37% | 2 |
| 6 (3) |  | Igor () | £451,742 | £641,280 | £1,752,139 | -54% | 2 |
| 7 (4) |  | The House Bunny () | £305,197 | £535,108 | £2,506,846 | -54% | 3 |
| 8 (6) |  | Taken (2008) | £260,342 | £521,535 | £6,046,921 | -51% | 5 |
| 9 (8) |  | Mamma Mia! () | £257,705 | £895,408 | £66,827,983 | -40% | 16 |
| 10 (5) |  | Mirrors () | £226,326 | £484,736 | £2,403,301 | -61% | 3 |
| 11 (7) |  | How to Lose Friends and Alienate People (2008) | £162,790 | £376,558 | £3,927,139 | -63% | 4 |
| 12 (12) |  | The Boy In the Striped Pajamas () | £110,790 | £235,358 | £3,975,047 | -44% | 7 |
| 13 (new) | | Heroes () | £107,090 | £107,090 | £107,090 | new | 1 |
| 14 (9) |  | City of Ember () | £102,429 | £177,975 | £1,147,808 | -64% | 3 |
| 15 (13) |  | Gomorrah (2008) | £91,320 | £178,907 | £620,717 | -33% | 3 |