| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Hancock () | £9,589,095 | £9,589,095 | £9,589,095 | new | 1 |
| 2 (new) |  | Kung-Fu Panda (2008) | £6,069,679 | £6,069,679 | £6,069,679 | new | 1 |
| 3 (1) |  | The Chronicles of Narnia: Prince Caspian () | £2,044,904 | £3,647,314 | £7,707,846 | -50% | 2 |
| 4 (2) |  | Wanted () | £1,240,801 | £2,788,578 | £6,602,633 | -67% | 2 |
| 5 (6) |  | Sex and the City (2008) | £282,561 | £791,837 | £25,489,747 | -52% | 6 |
| 6 (5) |  | Indiana Jones and the Kingdom of the Crystal Skull (2008) | £273,342 | £566,707 | £39,525,912 | -56% | 7 |
| 7 (4) |  | Adulthood (2008) | £270,102 | £595,205 | £2,997,371 | -58% | 3 |
| 8 (new) |  | The Mist () | £157,394 | £157,394 | £157,394 | new | 1 |
| 9 (3) |  | The Incredible Hulk () | £117,273 | £406,895 | £8,061,820 | -82% | 4 |
| 10 (7) |  | The Edge of Love (2008) | £109,742 | £335,733 | £877,246 | -58% | 3 |
| 11 (11) |  | Gone Baby Gone () | £50,730 | £129,938 | £1,622,547 | -41% | 5 |
| 12 (new) |  | Love Story 2050 () | £49,125 | £49,125 | £49,125 | new | 1 |
| 13 (new) |  | The Visitor () | £48,770 | £48,770 | £48,770 | new | 1 |
| 14 (10) |  | Thoda Pyaar Thoda Magic () | £41,605 | £108,732 | £239,032 | -68% | 2 |
| 15 (12) |  | Female Agents () | £36,303 | £88,665 | £157,077 | -47% | 2 |
| 16 (new) |  | Jaane Tu ... Ya Jaane Na () | £30,197 | £30,197 | £30,197 | new | 1 |
| 17 (new) |  | My Winnipeg (2008) | £9,662 | £9,662 | £9,662 | new | 1 |
| 18 (16) |  | A Complete History of My Sexual Failures (2008) | £7,092 | £21,045 | £33,817 | -44% | 2 |
| 19 (new) | | Muniyandi Vilangiyal Moondraamaandu (2008) | £4,910 | £4,910 | £4,910 | new | 1 |
| 20 (new) |  | Mes Amis Mes Amours (2008) | £2,260 | £2,260 | £2,260 | new | 1 |
| 21 (new) |  | Death Note: The Last Name () | £1,070 | £1,070 | £1,070 | new | 1 |
| 22 (18) |  | Son of Rambow (2008) | £305 | £-34,817 | £5,521,041 | 28% | 14 |